Endolymphatic hydrops presumption tests for patients with vestibular migraine

Abstract

Background The aetiology of vestibular migraine (VM) has not yet been defined; endolymphatic hydrops (EH) has been suggested as a candidate. Objectives This study aimed to clarify the relationship between VM and EH using neuro-otological tests, including the EH presumption test. Materials and methods Fourteen patients with VM underwent caloric testing, video head impulse test (vHIT), cervical and ocular vestibular evoked myogenic potential (cVEMP and oVEMP), and EH presumption tests such as the Futaki’s test and furosemide loading VEMP. Results Caloric testing was abnormal in two of the 14 cases (14.3%), and vHIT was abnormal in one of 12 cases (8.3%). Abnormal asymmetry ratios (ARs) of cVEMP and oVEMP were observed in two of 14 cases (14.3%) and six of 13 cases (46.2%), respectively. Futaki’s test results were positive in five of 14 cases (35.7%). Furosemide loading VEMP was positive in seven of 14 cases (50.0%). Nine patients (64.3%) were positive for at least one EH presumption test. Conclusions and significance EH is not a rare finding in VM; however, the ratio is less than that in Meniere’s disease.