Abstract
Recently we have isolated and purified an endogenous brain modulator (EBM) which competes with 3H-flunitrazepam (FNZP) for binding to the benzodiazepine (BZ) binding site1. In addition, we have also isolated and purified EBMs for the GABAA receptor as well as the glutamate receptor2. In light of numerous lines of evidence suggesting that taurine is involved in many important physiological functions such as in the development of the CNS3,4 in maintaining the structural integrity of the membrane5,6, in regulating calcium binding and transport7,8 and serving as an osmoregulator9,10 and inhibitory neurotransmitter11,13, it is highly desirable to determine whether endogenous modulators are also involved in the regulation of the taurine receptor. In this communication we present evidence to show that the taurine receptor is indeed also regulated by EBMs.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
