Abstract

The recent review on haemostasis in liver disease by Tripodi and Mannucci [ [1] Tripodi A. Mannucci P.M. Abnormalities of hemostasis in chronic liver disease: reappraisal of their clinical significance and need for clinical and laboratory research. J Hepatol. 2007; 46: 727-733 Abstract Full Text Full Text PDF PubMed Scopus (138) Google Scholar ] focused on the haemostatic balance in patients with liver cirrhosis. They suggested the presence of a delicate equilibrium between pro- and anticoagulation factors, which generates thrombin in a substantial equivalent amount in cirrhotic patients and controls, given a platelet count greater than 56 × 109/L−1[ [1] Tripodi A. Mannucci P.M. Abnormalities of hemostasis in chronic liver disease: reappraisal of their clinical significance and need for clinical and laboratory research. J Hepatol. 2007; 46: 727-733 Abstract Full Text Full Text PDF PubMed Scopus (138) Google Scholar ].

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