Abstract
Endogenous ATP, ADP and AMP were measured in both primary and FL human amnion cells. Measurements were made during hydrostatic pressure-treatment and during the period following release of pressure. FL amnion cells at 35 °C displayed an increase in ATP during pressure application and a rapid return to normal levels upon return to atmospheric pressure. There was no concomitant change in ADP and no AMP was detected. Primary amnion cells displayed little or no increase in ATP on pressure application. At 2 °C the rise in ATP in FL cells occurred at a more rapid rate than at 35 °C and the lower temperature effectively prevented the return to normal values upon release of pressure.
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