Endocrinopathies associated with hyperostosis frontalis interna

Abstract

The findings in seventeen women with hyperostosis frontalis interna have been tabulated and discussed. Evidence of some endocrine abnormality was frequently found but was possibly coincidental. There was great similarity of body build and symptomatology in this group of patients. As abnormal findings were numerous thorough laboratory study and detailed physical examination were essential; consultations with other specialists were frequently advisable. Frontal headache, asthenia, forgetfulness, vertigo, nervousness, obesity and poor vision were rather characteristic of this group. There was a high degree of morbidity with frequent remission and exacerbation of symptoms. No cause was found for this disease. It was limited almost entirely to the adult female. Some of the symptoms were probably due to cerebral atrophy. Useful hormonal, dietary and symptomatic treatment was diseussed.