Abstract

It is known that growth hormone, ACTH and cortisol are secreted in response to stress. Although the physiological role of pancreatic glucagon is not yet fully unterstood, it has recently been shown, that “stress” also leads to an increase in plasma glucagon concentration. dAnesthesia, as well as minor or major surgical procedures should provoke a “stress”-response. The development of sensitive radio-immunological methods allows the assay of a series of hormones in small plasma samples. Using these methods the presumed stress response could therefore be investigated in pediatric patients. The plasma concentrations of HGH, ACTH, cortisol and glucagon were determined before, during and after anesthesia pneumencephalography, cardiac catheterisation and minor or major surgery in children of different ages.

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