Environmental Health Perspectives | VOL. 102

Endocrine effects of prenatal exposure to PCBs, dioxins, and other xenobiotics: implications for policy and future research.

Publication Date Aug 1, 1994


Recent reports have suggested that environmental chemicals may be associated with endocrine alterations in people, wildlife, and experimental animals. Pharmacological investigations as well as natural poisoning episodes have led to the association between exogenous chemicals and alterations in multiple hormonal systems. Persistent environmental contaminants such as dioxins and PCBs have been shown to modulate the activities of several different hormones. The unborn child or the neonate may be at special risk from these chemicals because of rapid growth and development, in addition to enhanced exposure. Because most exposure to these persistent chemicals is via food, changes in dietary habits and/or reduced contamination of the food supply may be required.


Changes In Dietary Habits Exogenous Chemicals Pharmacological Investigations Endocrine Alterations Environmental Chemicals Implications For Policy Dietary Habits Special Risk Experimental Animals Unborn Child

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