Abstract
Craniopharyngioma is an intracranial congenital epithelial tumor growing along the pathway of the embryonic craniopharyngeal tube. The main clinical symptoms of patients with craniopharyngioma include high intracranial pressure, visual field defect, endocrine dysfunction, and hypothalamic dysfunction. At present, the preferred treatment remains the surgical treatment, but the recovery of endocrine and hypothalamic function following surgery is limited. In addition, endocrine disorders often emerge following surgery, which seriously reduces the quality of life of patients after operation. So far, research on craniopharyngioma focuses on ways to ameliorate endocrine dysfunction. This article reviews the latest research progress on pathogenesis, manifestation, significance, and treatment of endocrine disorders in patients with craniopharyngioma.
Highlights
Craniopharyngioma is a rare solid or mixed cystic epithelial tumor in the sellar and suprasellar region, accounting for 2–4% of intracranial tumors, which can be found in each age group [1]
Endocrine disorders are caused by primary tumor growth, surgical invasion, radiotherapy, pituitary fibrosis, etc
Gonadotropin deficiency in patients with craniopharyngioma increases the risk of poor prognosis; DI increases the risk of mortality and other complications
Summary
Craniopharyngioma is a rare solid or mixed cystic epithelial tumor in the sellar and suprasellar region, accounting for 2–4% of intracranial tumors, which can be found in each age group [1].
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