Abstract
Introduction. The diagnosis of sarcoidosis can be established when there is a compatible clinical-radiological picture together with pathohistological evidence of noncaseating epitheloid cell granulomas. Novelties in Diagnosis of Sarcoidosis. Pathohistological specimens can be obtained by conventional bronchoscopy with endobronchial and transbronchial lung biopsy, bronchoalveolar lavage, surgical procedures like cervical mediastinoscopy, diagnostic thoracotomy, video-assisted thoracoscopic surgery, and recently introduced endoscopic ultrasound techniques (endoscopic ultrasound-guided fine-needle aspiration and endobronchial ultrasound-guided transbronchial needle aspiration). Endobronchial ultrasound-guided transbronchial needle aspiration and endoscopic ultrasound-guided fine-needle aspiration have given a great contribution to diagnosis of sarcoidosis and present next diagnostic step after negative bronchoscopy. Conclusion. Reduction of surgical procedures in diagnosis of sarcoidosis, can be expected (first of all mediastinoscopy) by introducing endobronchial ultrasound-guided transbronchial needle aspiration and endoscopic ultrasound-guided fine-needle aspiration.
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