Abstract
Endobronchial brachytherapy alone or as part of a multimodal treatment, has a distinct role as palliative treatment in advanced lung cancer and as a curative treatment in selected cases of tumors confined to the bronchial wall. The safety and effectiveness of the procedure are optimized by a multidisciplinary approach that includes an expert bronchoscopist, a radiation oncologist and a radiation physicist, supported by a dedicated nurse and radiotherapy technician. Next we describe the methodology used in our center, where we have the experience of 7 years in treating 37 tumors in 31 patients. In 20 cases (64.5%), they had curative intent and 11 (35.5%) palliative intent. On 14 occasions, prior External Beam Radiation Therapy was used and in 7 cases was associated with other debulking methods. Overall, after a month of treatment, there was clinical improvement in 73.7% and endoscopic improvement in 87%. The complete response of the treated area for curative treatments was 70% at 1 month and 66.7% at 1 year. There were serious complications in 9.7% of cases.
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