Abstract

• Surface modification of the gold nanorod resulted in the end to alignment. • The calcium was detected in blood serum. • A paper-based strip was fabricated for the detection calcium. • The limit of detection of the sensor was found to be 14 nm. Point-of-care diagnostics devices are the next generation biosensors for the early detection of diseases. Nanotechnology can offer greater promise in this field. An end-to-end aligned gold nanorod is used as a sensor for the detection of calcium. The developed sensor is validated for calcium sensing in blood serum. The limit of detection of the developed sensor is 14 nM. Paper-based strips are fabricated using the developed sensor for the detection of calcium.

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