Encephalopathy and hearing loss in a young woman with demyelinating lesions on her brain MRI

Abstract

A 26-year-old woman developed vertigo. She was seen by an audiologist and underwent a pure-tonal audiogram, which showed severe right perceptive hearing loss, mainly in the low frequencies with a speech reception threshold of −70 dB. She also developed headaches and her family noticed that she was forgetful. A neurologist in the local hospital ordered a brain MRI (Fig. 1), which showed multiple demyelinating subcortical and periventricular lesions. In addition, lesions in the center of the corpus callosum, hyperintense on T2-weighted MRI and hypointense on T1-weighted MRI, were noted. Treatment with 1000 mg/daily methylprednisolone was started but the patient became psychotic and was transferred to our Referral Center. Encephalopathy and hearing loss in a young woman with demyelinating lesions on her brain MRIJournal of Clinical NeuroscienceVol. 17Issue 11PreviewD. Susac’s syndrome. Full-Text PDF