Abstract
Single-cell encapsulation using metal-phenolic networks (MPNs) is an emerging technique to protect cells from stressors. Until now, the MPN coatings have been only applied to some bacteria, yeast, and mammalian cells. To further demonstrate their versatility, we herein coat Chlamydomonas reinhardtii with the network consisting of tannic acid and iron(III). The encapsulation served as a mechanical barrier, which delayed proliferation of the coated cells. Furthermore, we investigated the adsorption of tannic acid onto the surface of C. reinhardtii and identified the optimum concentration to achieve partial coverage on the algae's surface. Finally, we explored the effect of MPN coating for flocculation-enhanced algae harvesting. Overall, the results demonstrate that the cell encapsulation technique using metal-phenolic networks is applicable to the C. reinhardtii, which is promising for the surface engineering of the green algae for energy harvesting and biomedical applications.
Highlights
Metal-phenolic networks (MPNs) can be used as versatile coatings [1] with applications in fields such as drug delivery [2], dental hyper sensitivity [3], enzyme immobilization [4] and marine anti-fouling [5]
We investigated the adsorption of tannic acid onto the surface of C. reinhardtii and identified the optimum concentration to achieve partial coverage on the algae's surface
The results demonstrate that the cell encapsulation technique using metal-phenolic networks is applicable to the C. reinhardtii, which is promising for the surface engineering of the green algae for energy harvesting and biomedical applications
Summary
Metal-phenolic networks (MPNs) can be used as versatile coatings [1] with applications in fields such as drug delivery [2], dental hyper sensitivity [3], enzyme immobilization [4] and marine anti-fouling [5]. The ability to engineer specific and desired properties into materials has led to this tremendous interest, and researchers have continuously expanded the coating-material library throughout the last decade [6]. From this library, it is often possible to choose a coating with a set of properties tailored for the intended application. A TA-Fe (III) coating exhibits pH response [7], UV-C absorption [8], transport barricading [9], and mechanical enhancement [10], which makes for an interesting coating to cells.
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