Abstract
A 3,5-dimethylphenylcarbamate derivative of cellulose immobilized onto the aminopropyl-modified silica gel was used as a chiral stationary phase and separation of five enantiomers was successfully performed by a home-made chiral capillary liquid chromatography system. Different chromatographic parameters such as resolution, column efficiency, and retention time were comparatively investigated using three chiral stationary phases with different coatings. The key factors which may influence the performance of the chiral stationary phases were evaluated by varying the composition of the mobile phase and its flow rate. It was illustrated that the self-installed chiral separation system was characterized by simplicity, high resolution, ease for practical usage, and could be handily applied for enantioseparation at the conventional laboratory.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
