Enantioselective synthesis of α,β-diamino ester derivatives: memory of chirality in imino-aldol reactions

Abstract

A simple strategy for the synthesis of chiral α,β-diamino ester derivatives in good yields and ee (up to 92%) utilizing the ‘memory of chirality’ concept is reported. This methodology has been extended for the enantioselective synthesis of substituted aziridines with excellent ee (92%).