Abstract
AbstractThe first enantioselective synthesis of cyclic N,S‐ketals having tetrasubstituted chiral center through intramolecular cyclization between carbonyl compounds and aminothiols has been developed. The reaction of fluoroalkyl ketones with aminobenzenethiols using a chiral imidazoline−phosphoric acid catalyst afforded products in high yields with high enantioselectivity. The observed enantioselectivity is explained using preliminary mechanistic information.magnified image
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
