Enantioselective Synthesis of β-Amino Acids via Stereoselective Hydrogenation of β-Aminoacrylic Acid Derivatives

Abstract

This chapter describes recent developments in the stereoselective hydrogenation of β-aminoacrylic acid derivatives en route to enantiopure β-amino acids. Some of the methods highlighted include Rhodium complexes with chiral phosphorus bidentate ligands Rhodium complexes with chiral phosphorus monodentate ligands Ruthenium complexes with chiral phosphorus bidentate ligands