Abstract
A nice approach for enantioselective ring expansion of monoactivated methylenecyclopropanes has been developed. The use of MgI2 as Lewis acid starting material and CP-IndaBOX as chiral ligand afforded the best results, giving adducts in the range of 49-86% ee. Of the tested imine substrates, electron-withdrawing groups on the aryl ring succeeded in yielding higher selectivities than substrates with strongly electron-donating groups.
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