Abstract
Chiral monodentate phosphoramidite ligands were conveniently prepared from 1,1′-bi-2-naphthol (BINOL) and (S)-pyrrolidine in good yields, which were effective chiral ligands in the enantioselective rhodium-catalyzed hydrogenation of dehydroamino esters and enamides at low hydrogenation pressure. High conversion rate (up to 99% for dehydroamino esters and enamides) and good enantioselectivity (up to 96.3% ee for dehydroamino esters and 91.7% ee for enamides) were obtained.
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