Abstract
The authors developed a new approach to cascade catalysis. Using a single imidazolidinone catalyst, involving iminium (LUMO-lowering) and enamine (HOMO-raising) catalysis, a large diversity of nucleophiles (furans, thiophenes, indoles, butenolides, hydride sources, tertiary amino lactone equivalents) and electrophiles (fluorinating and chlorinating reagents) undergo highly enantioselective sequential addition with α,β-unsaturated aldehydes (÷99% ee in all cases).
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
