Abstract
Recently in the Journal of the American Chemical Society , Buchwald and co-workers achieved enantioselective installation of a methyl group through copper-catalyzed hydromethylation. They demonstrated the utility of this method through the methylation of several olefin substrates, including drug molecules. Recently in the Journal of the American Chemical Society , Buchwald and co-workers achieved enantioselective installation of a methyl group through copper-catalyzed hydromethylation. They demonstrated the utility of this method through the methylation of several olefin substrates, including drug molecules.
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