Abstract

AbstractThe first copper‐catalyzed intermolecular enantioselective decarboxylative propargylic alkylation of propargylic esters with β‐keto acids as surrogates of ketones has been successfully developed by using a ketimine P,N,N‐ligand. High yields and excellent enantioselectivities (up to 98% ee) have been achieved under the mild reaction conditions.magnified image

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