Abstract
Chiral dicationic SEGPHOS–Pd(II) complex gives high chemical yield, ( E)-olefin selectivity, anti-diastereoselectivity, along with high enantioselectivity even with less reactive mono- and 1,2-disubstituted olefins in this much less reactive ketone-ene reactions. The high levels of enantioselectivity not only in carbonyl-ene but also in Friedel–Crafts reactions stem from the effective shielding with diphenyl groups on phosphines caused by the narrow dihedral angle of metal complexes with SEGPHOS.
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