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https://doi.org/10.1039/c9ra05532k
Copy DOIJournal: RSC Advances | Publication Date: Jan 1, 2019 |
Citations: 14 | License type: CC BY 3.0 |
Enantioselective bromination of axially chiral cyanoarenes bearing high intrinsic rotational barriers via dynamic kinetic resolution using bifunctional organocatalysts is reported. Sequential addition of a brominating reagent in several portions at an optimized temperature was effective in accomplishing high enantioselectivities.
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