Abstract
The first catalytic enantioselective amination of silylketene acetals with ( N-arylsulfonylimino)phenyliodinanes is described. The reaction of silylketene acetals derived from methyl phenylacetates with [ N-(2-nitrophenylsulfonyl)imino]phenyliodinane (NsN = IPh) under the catalysis of dirhodium(II) tetrakis[ N-tetrachlorophthaloyl-( S)- tert-leucinate], Rh 2( S-TCPTTL) 4, proceeds in benzene at room temperature to give N-(2-nitrophenylsulfonyl)phenylglycine derivatives in high yields and with enantioselectivities of up to 99% ee.
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