Abstract
AbstractAn enantioselective organocatalytic addition of sodium bisulfite to (E)‐nitroalkenes has been developed by using a chiral bifunctional organocatalyst. The present methodology provides a variety of chiral β‐nitroethanesulfonic acid compounds (17 examples) with excellent results: up to 99 % yield and excellent enantioselectivity (up to 96 % ee). The reaction tolerates (hetero)aryl and alkyl substituents on the β‐nitroalkenes, and β,β‐disubstituted nitroalkenes.
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