Abstract
AbstractAxially chiral biaryls are widespread in natural products, and often utilized as chiral ligands or catalysts in asymmetric catalysis. Driven by the demand of efficient assembly of axial biaryls, we describe herein a novel atropoenantioselective synthesis of biaryls via a ruthenium catalyzed hydrogen‐transfer reductive amination and dynamic kinetic resolution process. This protocol enriches the diversity of axial biaryl amine‐alcohols bearing various substituents and functional groups.
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