Abstract

Direct enantiomeric resolution of the germacrene-D derivative, (5E,7S*,9S*)-9-hydroxy-7-isopropyl-4,10-bis(methyIene)-5-cyclodecen-1-one, was carried out by HPLC with a chiral stationary phase. This method showed that germacrene-D contained in ylang ylang oil was 98% e.e., whereas germacrene-D extracted from Solidago altissima L. was almost racemic.

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