Abstract
The Northwestern University Clinical and Translational Sciences Institute (NUCATS) was launched in 2007 to create a central hub supporting clinical and translational science (CTS) across numerous schools at Northwestern University, our three main clinical partners (Northwestern Memorial Healthcare Corporation, Ann and Robert H. Lurie Children's Hospital, and The Rehabilitation Institute of Chicago), community and industry stakeholders, and beyond. NUCATS is designed to support the entire spectrum of CTS, from basic discovery through clinical trials to community-based research, dissemination and implementation, regardless of disease area. Funded by a Clinical and Translational Award (CTSA) from the NIH, and supported by extensive institutional resources, NUCATS has become an innovation leader in several key areas of CTS. Here we highlight the critical contributions an enterprise data warehouse can make to advancing translational science and quality clinical care to enable a learning healthcare system. Central to the success of our EDW has been the governance model and data structure that have enabled rapid advances in CTS, several examples of which we provide.
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