EMULGEL EMERGENT SYSTEMS: AT A GLANCE FOR TOPICAL DRUG DELIVERY

Girjesh Vishwakarma,Aakash Singh Panwar

doi:10.22159/ajpcr.2022.v15i3.43876

Girjesh Vishwakarma, Aakash Singh Panwar

Open Access

https://doi.org/10.22159/ajpcr.2022.v15i3.43876

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Abstract

Emulgels have been emerged both in cosmetics and pharmaceutical preparations. When gel and emulsion are used in the combined form, they are referred to as Emulgel. Emulgel is a promising drug delivery system for the delivery of hydrophobic drugs. Emulgel is an emulsion that is gelled by mixing it with gelling agents. Many advantages of gels have the major limitation of delivery of hydrophobic drugs. Hence, the emulsion-based approach is being used to overcome this limitation. Emulgel is an interesting topical drug delivery system as it has a dual release control system, i.e., gel and emulsion. The use of gels and emulsions as combined dosage form results in the formation of emulgel showing dual release. With this approach, polymers with enhanced effect in release patterns have emerged, providing sustained and controlled release. They are generally applied for antiseptics, antifungal agents, skin emollients, and protectants. The activity of topical preparation confides in various factors such as drug solubility, lipophilicity, contact time to the skin, and permeability. Emulgels have numerous advantages in dermatology, such as being thixotropic, greaseless, easily spreadable, easily removable, emollient, nonstaining, long shelf life, bio-friendly, transparent and pleasing appearance. Emulgel is being used to deliver analgesics, anti-inflammatory, antifungal, anti-acne drugs, and various cosmetic formulations with a wide range to explore.

Highlights

Topical drug delivery systems skin serves as one of the most easy to get to routes for drug administration
The topical drug delivery system has been used for centuries to manage local skin disorders and is a generalized drug delivery system wherever in the body through ophthalmic, rectal, vaginal, and skin as a topical route
Ground glass is fixed in the block. 2 g of emulgel is placed on it and covered with another glass slid as a sandwich

Summary

Introduction

Topical drug delivery systems skin serves as one of the most easy to get to routes for drug administration. The main disadvantage of a topical drug delivery system as a gel is that hydrophobic moiety cannot quickly be delivered through the skin [3].

Results

Conclusion