Abstract
Empyema caused by MRSA ST398 with Atypical Resistance Profile, Spain
Highlights
To the Editor: We report a case of empyema caused by methicillin-resistant Staphylococcus aureus (MRSA) sequence type ST398 in a 79-year-old man in Spain who had severe chronic obstructive pulmonary disease
All 3 MRSA isolates were typed as sequence type (ST) 398, spa-type t011, SCCmecV, and agrI
All 3 MRSA isolates were negative by PCR for the Panton-Valentine leukocidin, toxic shock syndrome toxin 1, and exfoliative toxins A and B
Summary
To the Editor: We report a case of empyema caused by methicillin-resistant Staphylococcus aureus (MRSA) sequence type ST398 in a 79-year-old man in Spain who had severe chronic obstructive pulmonary disease. The 3 MRSA isolates were typed (multilocus sequence typing-, spa-, staphylococcal cassette chromosome [SCC] mec-, and agr-typing, in addition to pulsed-field gel electrophoresis [PFGE]), likewise, the antimicrobial drug–resistance phenotypes and genotypes, and virulence genes were determined [1,2]. The 3 isolates had the same resistance phenotype, including to β-lactams, tetracycline, clindamycin (but not erythromycin), ciprofloxacin, and levofloxacin.
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