Abstract
It has been clearly shown that in certain species of mammals, such as the opossum1 and the rabbit,2 there is little if any emptying of the gall bladder after meals, although Walsh reports that partial evacuation in the rabbit may be induced by cholecystokinin.3It is of especial interest, therefore, to ascertain the rate of emptying of the gall bladder in animals nearest man. Through the courtesy of Dr. J. C. McKinley, 5 specimens of Macacus rhesus were made available for study, and the gall bladder of each visualized: first, by intravenous injection of tetraiodophenolphthalein, and afterwards, by direct introduction of lipiodol at the time of laparotomy.Two of the animals (both of them females) failed to exhibit shadows after the Graham test and failed, subsequently, to empty the lipiodol after a meal of egg yolk. In one of these there was a supracolic peritonitis. In the other, as revealed by serial sections, there was a subacute or chronic cholecystitis with marked infiltration of plasma cells and lymph...
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