Empiric antibiotic treatment of suspected chronic endometritis does not improve sustained implantation rates following failed euploid frozen embryo transfer (FET)

Abstract

Chronic endometritis (CE) is associated with lower implantation rates in patients with recurrent implantation failure1. Some studies have demonstrated an improvement in pregnancy outcomes following antibiotic treatment for CE. Diagnosis of CE requires a procedure, typically an endometrial biopsy or dilation and curettage, in order to obtain a histologic specimen2. Some clinicians have moved towards empiric antibiotic treatment of suspected chronic endometritis for patients with a prior implantation failure.