Abstract

CITATION: Schwartz, I. S., et al. 2019. Emergomyces : the global rise of new dimorphic fungal pathogens. PLoS Pathogens, 15(9):e1007977, doi:10.1371/journal.ppat.1007977.

Highlights

  • In some regions, such as southern Africa, this disease, emergomycosis, is the most commonly diagnosed dimorphic fungal infection

  • In 2013, following the introduction of molecular identification procedures in some South African laboratories, a dimorphic fungus most closely related to Ea. pasteuriana was found to be the cause of a disseminated mycosis in patients with advanced HIV disease [4]

  • A new genus, Emergomyces, was created to accommodate Emmonsia-like systemic dimorphic pathogens related to Es. pasteurianus and characterized in the thermodependent phase by small yeast cells with narrowbased buds [8, 9]

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Summary

Introduction

In some regions, such as southern Africa, this disease, emergomycosis, is the most commonly diagnosed dimorphic fungal infection. In 2013, following the introduction of molecular identification procedures in some South African laboratories, a dimorphic fungus most closely related to Ea. pasteuriana was found to be the cause of a disseminated mycosis in patients with advanced HIV disease [4]. Infection with this fungus has been established to comprise the most frequently diagnosed dimorphic mycosis in South Africa [5,6,7].

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