Abstract
In the past few years, emergent disease episodes have increased; nearly all have involved zoonotic or species-jumping infectious agents. Because there is no way to predict when or where the next important new zoonotic pathogen will emerge or what its ultimate importance might be, investigation at the first sign of emergence of a new zoonotic disease is particularly important. Such investigation may be described in terms of a discovery-to-control continuum: from recognition of a new disease in a new setting to complex phases involving the hard science disciplines pertaining to discovery, the epidemiologic sciences pertaining to risk assessment, and activities pertaining to risk management. Today, many activities involving zoonotic disease control are at risk because of a failed investigative infrastructure or financial base. Because zoonotic diseases are distinct, their prevention and control will require unique strategies, based more on fundamental research than on traditional approaches. Such strategies require that we rebuild a cadre of career-committed professionals with a holistic appreciation of several medical and biologic sciences.
Highlights
Rates To determine the expected demographics, rates of hospitalization, and international travel among patients with Salmonella Infantis infections compared with patients with infections caused by other common nontyphoidal Salmonella serotypes, we analyzed data collected through the Foodborne Disease Active Surveillance Network (FoodNet; https://www.cdc.gov/foodnet/index.html) during 2012–2015
The 2014 and 2015 St. Louis encephalitis virus (SLEV) isolates are genetically distinct from the 2003 Imperial Valley, California, strain that was isolated before the 11-year absence of SLEV activity in the state [49]. These results suggest there was likely a single introduction of SLEV into the United States from South America, and possibly Argentina, no later than November 2014, the earliest dated sample from which SLEV was isolated in Arizona and that the virus spread in the summer of 2015 from Arizona to California [49]
Investigation of Feeder Rats Owned by the Patient Because the patient kept feeder rats at home and these rats are a known source of Seoul virus (SEOV) infection, the rats were collected for source investigation
Summary
Rates To determine the expected demographics, rates of hospitalization, and international travel among patients with Salmonella Infantis infections compared with patients with infections caused by other common nontyphoidal Salmonella serotypes, we analyzed data collected through the Foodborne Disease Active Surveillance Network (FoodNet; https://www.cdc.gov/foodnet/index.html) during 2012–2015. Begun in 1996, FoodNet has conducted active, population-based surveillance for culture-confirmed cases of infection caused by 9 pathogens transmitted commonly through food, including Salmonella. The FoodNet surveillance area includes 15% of the US population; these data are used to estimate the burden of US foodborne illnesses, hospitalizations, and deaths [1]. L(+) tartrate+, Blockley, Anatum, Mississippi, and Panama. These 20 serotypes represented 69% of nontyphoidal Salmonella isolates reported to FoodNet in 2015
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