Abstract
Coxsackievirus A6 emerged as one of the predominant causative agents of hand, foot and mouth disease epidemics in many provinces of China in 2013 and 2015. This virus strain accounted for 25.9% of mild and 15.2% of severe cases in 2013 and 25.8% of mild and 16.9% of severe cases in 2015.
Highlights
Coxsackievirus A6 emerged as one of the predominant causative agents of hand, foot and mouth disease epidemics in many provinces of China in 2013 and 2015
The Study Since June 2009, clinical specimens must be collected from all severe HFMD cases, and the first 5 reported mild cases in each county of China every month and are tested for enteroviruses at local CDCs using PCR [10]
For specimens testing positive for other enteroviruses, further serotyping is not conducted as a routine practice, but some local CDCs with more laboratory capacity may select a subset of these specimens to test on the serotype at their own discretion, especially when the proportion of other enteroviruses detected was relatively high
Summary
Coxsackievirus A6 emerged as one of the predominant causative agents of hand, foot and mouth disease epidemics in many provinces of China in 2013 and 2015. The Study Since June 2009, clinical specimens must be collected from all severe HFMD cases, and the first 5 reported mild cases (case classification criteria in the online Technical Appendix, https://wwwnc.cdc.gov/EID/article/24/10/171953-Techapp1.pdf) in each county of China every month and are tested for enteroviruses at local CDCs using PCR (online Technical Appendix) [10]. For specimens testing positive for other enteroviruses, further serotyping is not conducted as a routine practice, but some local CDCs with more laboratory capacity may select a subset of these specimens to test on the serotype at their own discretion, especially when the proportion of other enteroviruses detected was relatively high.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
