Emerging Energies for Focal Ablation of Prostate Cancer

Abstract

Four energy modalities are routinely used for focal therapy (FT) in expert centers: cryotherapy, high-intensity focused ultrasound, vascular-targeted photodynamic therapy, and brachytherapy. In this section, we review the emerging FT energies that are suitable for use in the treatment of localized prostate cancer. Irreversible electroporation is a nonthermal energy that is effective in destroying the cancer cells, with the advantage of sparing surrounding tissue such as blood vessels and neurons, hopefully leading to better functional preservation.