Abstract

Introduction: Hereditary angioedema (HAE) is a genetic disorder resulting in low or dysfunctional C1 inhibitor (C1-INH): Type 1/2 HAE and/or dysregulation of bradykinin production: HAE with normal C1INH (HAEnC1-INH). HAE is characterized by recurring, painful swelling occurring in any part of the body. Laryngeal swelling can be fatal and abdominal swelling is very painful. Consequently, HAE patients often require emergency room (ER) visits.

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