Abstract
There is increasing evidence that prolonged seizures are best stopped with early treatment. Although it is well accepted that benzodiazepines are the first line of therapy, intramuscular paraldehyde is used in many parts of the world when intravenous access is not achieved or available.1 Whilst efficacious, use of intramuscular paraldehyde in neonates and young children can result in sciatic nerve injury, skin sloughing, and sterile abscesses.2 An alternative treatment, transmucosal benzodiazepine, is effective, but there are concerns about potential routes of delivery.
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