Abstract
Hemophilia is a severe congenital bleeding disorder associated with both spontaneous and traumatic bleeding episodes that can require emergent medical evaluation. Many persons with hemophilia (PWH) utilize the emergency department for the initial management of acute bleeding events. Prompt administration of factor replacement products is crucial in controlling acute bleeds and minimizing potential associated morbidity. PWH who have inhibitory antibodies can be especially difficult to treat, as they often require by-passing agent therapies to obtain hemostatic control. Although consultation with an experienced hematologist is always warranted, initial management of acute complications in hemophilia is emergent, which necessitates emergency care providers to have a strong understanding of the current treatment principles in this complex condition.
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