Abstract
Emergence of New Delhi Metallo-β-Lactamase, Austria
Highlights
To the Editor: Extended-spectrum β-lactamase–producing Enterobacteriaceae strains have emerged as a major public health problem throughout the world, in India and Pakistan
NDM-1 shares very little identity with other metallo-β-lactamase enzymes; Enterobacteriaceae isolates with NDM-1 show high resistance to most commonly used antibacterial agents [4]
The emergence of NDM-1 poses the risk of plasmid-mediated transfer of the carbapenemase enzyme blaNDM-1 between different bacterial strains, which could lead to serious public health issues [3,5]
Summary
To the Editor: Extended-spectrum β-lactamase–producing Enterobacteriaceae strains have emerged as a major public health problem throughout the world, in India and Pakistan. NDM-1 shares very little identity with other metallo-β-lactamase enzymes; Enterobacteriaceae isolates with NDM-1 show high resistance to most commonly used antibacterial agents [4]. Most NDM-1 patients in Europe and the United States had received medical care in India or Pakistan before isolation of the strain. The emergence of NDM-1 poses the risk of plasmid-mediated transfer of the carbapenemase enzyme blaNDM-1 between different bacterial strains, which could lead to serious public health issues [3,5].
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