Abstract
We report two patients with atopic dermatitis who developed methicillin-resistant Staphylococcus aureus (MRSA) skin infections resistant to clindamycin and trimethoprim-sulfamethoxazole requiring repeated linezolid treatment. For one patient and family members who received an aggressive regimen of staphylococcal decolonization, including intranasal mupirocin, dilute bleach baths, and bleach cleansing of household items and surfaces, subsequent culture results demonstrated methicillin-susceptible S. aureus colonization and infection. These findings underscore the challenges presented by multiresistant MRSA infections in children with atopic dermatitis.
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