Abstract
Campylobacter jejuni (C. jejuni) is considered as an opportunistic zoonotic pathogen that may cause gastroenteritis in humans and other animals. Wild birds may be as potential vectors of C. jejuni around urban and suburban areas. Here, 520 samples were collected from 33 wild bird species in urban and suburban areas, Beijing. In total 57 C. jejuni were isolated from seven species. It was found that Nineteen (33.33%, 19/57) isolates were resistant to at least one of 11 antibiotics, especially streptomycin (36.84%) and four isolates resistant to all. Nineteen (33.33%, 19/57) isolates were multi-drug resistance. Multilocus sequence typing (MLST) analysis of the isolates showed that 36 different sequence types (STs) belonged to four Clonal complexes and unassigned. Twenty STs (55.56%) and six alleles among them were first detected. Virulence genes including flaA, cadF, and the cytolethal distending toxin (CDT) gene cluster, were detected in all isolates, but truncated cdt gene clusters only detected in the isolates from the crow, daurian jackdaw and silver pheasant. In conclusion, it was the first detection of C. jejuni involved truncated cdt gene clusters from the silver pheasant. These wild birds around urban and suburban areas may pose potential public health problems as reservoir vectors of C. jejuni.
Highlights
Campylobacter jejuni is a gram-negative spiral rod bacterium that causes gastroenteritis in humans and other animals
C. jejuni was isolated from 57 samples (10.96%, 57/520) including seven species
Rock pigeon (Columba livia), had relatively lower positive rate than others. This is the first time that C. jejuni has been isolated from black swan (Cygnus atratus) (Table 1)
Summary
Campylobacter jejuni is a gram-negative spiral rod bacterium that causes gastroenteritis in humans and other animals. The process of infection involved in adhesion, colonization, invasion and toxin production, especially, flaA genes, cadF genes, and cdt gene clusters are necessary for cell pathology and virulence in humans (Wei et al, 2018). These three virulence genes are frequently researched in isolates from various hosts, especially humans and poultry. We investigated the prevalence, genetic diversity (Multilocus sequence typing), antimicrobial resistance patterns and virulence genes (flaA genes, cadF genes, and cdt gene cluster) of Campylobacter in wild birds in Beijing, China
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