Abstract
From September 2014 to March 2015, 23 outbreaks of norovirus (NoV) acute gastroenteritis occurred in Jiangsu, China. Partial sequencing of the NoV capsid gene suggested that 16 of the 23 outbreaks were related to a new GII.17 variant. This variant was first detected in sporadic specimens in October 2014, and became predominant in February 2015. Analysis of the RNA-dependent RNA polymerase (RdRp), and complete capsid including the protruding domain P2 sequences confirmed this GII.17 variant as distinct from previously identified GII variants.
Highlights
Norovirus (NoV) is a major cause of viral gastroenteritis and is the main aetiological agent ofoutbreaks of acute gastroenteritis [1]
In late 2014, the Emergent Public Health Event Information Management System (EPHEIM) in Jiangsu province observed an increase of NoV outbreaks compared with previous seasons
An acute gastroenteritis outbreak was defined as ≥20 cases of vomiting and/or diarrhoea associated with a common exposure
Summary
Norovirus (NoV) is a major cause of viral gastroenteritis and is the main aetiological agent ofoutbreaks of acute gastroenteritis [1]. NoV has rarely been reported as a major genotype causing diarrhoea. In late 2014, the Emergent Public Health Event Information Management System (EPHEIM) in Jiangsu province observed an increase of NoV outbreaks compared with previous seasons. Data from these outbreaks indicated that this increase was associated with the emergence of a new variant of GII., which was rarely reported in China before 2014. Surveillance of NoV in both outbreak and sporadic cases was conducted from September 2014 to March 2015 to study the molecular epidemiology characteristics of GII.17associated diarrhoea in Jiangsu province, China
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