Abstract

1 Demographic Changes 2 International Travel and Commerce 3 Societal Changes 4 Changes in Technology 5 Land-Use Patterns and Ecological Change 6 Microbial Adaptation and Change 7 Breakdown of Public-Health Infrastructure 8 Intent to do Harm: Bioterrorism 9 Infectious Origins of Chronic Diseases 10 Summary Keywords: bacterial infectious diseases-emergence and resurgence; infectious diseases-leading cause of death in developing countries; dramatic increases in international travel and commerce and infectious disease emergence; technology changes and emerging newly recognized pathogens; diarrheal illness outbreaks in child-care centers; advent of highly active antiretroviral therapy (HAART)-major impact on opportunistic infections; ecological changes and tick-borne diseases; microbial adaptation and change

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