Abstract
In Reply.— Iffy's letter links time in the menstrual cycle and location of the embryo as principle factors in the occurrence of ectopic pregnancy. His remarks on mechanisms—reflux and flux—follow more than 20 years of attention to understanding the origins of tubal and abdominal pregnancy. Indeed, our manipulations of primate embryos during a variety of laboratory studies have been associated with five ectopic (two tubal and three abdominal) pregnancies during the past 15 years at the National Institutes of Health. 1,2 During that same interval, I observed only one spontaneous ectopic (tubal) pregnancy in a rhesus monkey, unassociated with experimental activities; the total number of pregnancies in those years would exceed 3,000. The induced cases probably resulted from retrograde lavage being used to collect eggs and embryos, either because we missed them or because normal gamete/embryo transport was disrupted by surgical trauma to the reproductive tract. My anecdotal observations fit
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: JAMA: The Journal of the American Medical Association
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
