Abstract

Abstract This study explores the potential of the natural and cost-effective method of wound healing using Alternanthera sessilis by an in vitro study (using fibroblast L929 cells). Gram-positive bacteria Staphylococcus aureus shows a zone of inhibition of 20 mm at 60 µg concentration in the antibiogram profile against the zinc oxide nanoparticles (ZnONPs) wetted in fabrics synthesized from the Amaranthaceae family. Through characterization studies of the AS-ZnONPs, it was found that UV–visible spectra show a peak in the range of 350–460 nm, Fourier transform infrared spectroscopy spectra show a correlation peak in the range of 340–4,500 cm−1, scanning electron microscope with electron diffraction analysis results in a peak in the range of 7.8–9.4, and high-resolution transmission electron microscope, which exposes the morphological character (diamond shape in a black and white background), shows a peak at 200 nm. This work shows that the leaf extract of A. sessilis might support the ancient method of wound healing.

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