Abstract
The entity by which something is produced specifically is known as Nidana. It is Adikarana- means to prime factor among diverse determinants of disease. Illness is because of different causes and its effect is seen in the form of linga-symptoms of a disease. Because of which ancient seers propounded the Trisutra Ayurveda, namely hetu-linga and Aushadha. In many contexts of Samhitha, while Nidana engendering Vyadhi, Guna- properties are described, because properties have considerable importance in pharmacologi-cal, pathological action. One such context is Kushta Nidana, where aetiology delineated as Sheetoshna Vyatyasa - interchange use of cold and hot properties. This article foregrounded on the proposition of Kar-ya-Karana-Vada of Ayurveda, to throw light on the expository of Gunas in manifesting Kushta.
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