ELİT TÜRK GÜREŞÇİLERİNİN ANJİOTENSİN I-DÖNÜŞTÜRÜCÜ ENZİM GEN POLİMORFİZMİ VE VO2MAX DÜZEYLERİ İLE ATLETİK PERFORMANS ARASINDAKİ İLİŞKİNİN BELİRLENMESİ

Abstract

The polymorphism of angiotensin I-converting enzyme gene is one of the important genes associated with physical activity, The aim of this study is to determine whether there is a relationship between ACE I/D gene polymorphism and athletic performance and genotype distribution of the ACE gene and maximum oxygen consumption (Vo2max) in the elite Turkish wrestlers. ACE I/D gene polymorphism is investigated in 46 elite Turkish wrestlers and 58 healthy sedentary individuals. Vo2max values in elite wrestlers were measured by a progressive shuttle run test. DNA of elite wrestlers and sedentary individuals was obtained from peripheral blood. The allele frequencies and genotype distribution of ACE I/D gene polymorphism determined by polymerase chain reaction. Allele frequencies and genotype distribution of ACE I/D gene polymorphism in the elite wrestlers and sedentary individuals were compared and no significant difference was found between elite wrestlers and sedentary individuals (P>0.05). There was also no difference between the genotype distribution of the ACE I/D gene polymorphism and Vo2max levels in the elite wrestlers (P>0.05). It was determined that Vo2max showed similar distribution in elite wrestlers with DD, ID and II genotypes. The present study demonstrated that there was no significant relationship between the ACE I/D gene polymorphism and sports performance and genotypes of ACE I/D gene polymorphism and Vo2max in elite Turkish wrestlers.