Abstract
Results from an interspecies scaling study of the elimination half-lives of the anxiolytic GB-115 and the antipsychotic dilept in rats, rabbits, and humans are presented. The elimination half-lives of the studied drugs are calculated in real (chronological) and corrected time (pharmacokinetic). Elimination half-lives in animals and volunteers are compared. Rabbits are found to be a better scaling model for GB-115 although a single preference for dilept was not found.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
